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pentobarbital will reduce the extent or effect of saxagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.pentobarbital will reduce the extent or effect of eltrombopag by impacting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Check.buprenorphine subdermal implant and pentobarbital both of those enhanc